Graduated from Brandeis University (Waltham, Massachusetts, USA).

Following undergraduate training, went on to earn Master's degree in drama from New York University.

Engaged to Daniel Zelman. [1998]

Is severely allergic to flowers and perfumes.

Was named one of the 50 Most Beautiful People by People Magazine in 2002.

Named TV Guide's "best dressed woman" in 2003

Was Rhode Island's Junior Miss in 1986.

Gave birth to a son, Roman Walker Zelman, in Los Angeles, weighing 5lbs 14oz. [April 7, 2004]

Beat Nicollette Sheridan for the role of "Grace Adler" on "Will & Grace" (1998) at the final auditions.

Although her son Roman is not deaf, she has taught him a few words in sign language to make communication easier for him until he's more able to talk.

Appeared with her "Will & Grace" (1998) co-star Shelley Morrison in an episode of "Prey" (1998): "Revelations". While Messing was a steady member of the cast, Morrison only had a guest-starring role.

She has owned 3 mansions in Hyde Park, Piccadilly Circus, and Belgravia in London, England since January 1, 1986.

Played the leading role as Sandy in her high school musical production of "Grease".

Replaced Sherilyn Fenn as the female lead in "Prey" (1998).

Favorite food is pepperoni pizza.

Loves gambling (blackjack).

Would have been litigator if she wasn't an actress.