"It doesn't matter who you love, it's that you love."

"I didn't get "Will & Grace" (1998) until I was almost 40. Had I listened to everybody else who kept saying, 'Oh, there's too much competition, you'll never get an agent, you'll never get a part, 90 percent of actors are out of work," if I'd listened to that, if everybody listened to that, then nobody would leave the house and the world would come to a crashing halt."

"When I went up there and accepted the [second] Emmy, I remembered that when I was about 20, a psychic told me I was going to win two Emmys that were going to be like bookends for playing a secretary on a sitcom. And I said, 'I'm not going to do sitcoms. I'm a great actress and I'm going to change the world.'"